Question by : Is it safe to take Pseudo-Ephedrine and then exercise?
I took 240mg of Pseudo-Ephedrine is it OK to do cardio vascular exercises now? Or should I avoid them and do them after the medication wears off?
I have taken it and slept before a lot of times. I’m not allergic to it. I just sometimes get “wired” from it and I’m just wondering if it’s safe to do cardio vascular exercise while on it? I do not have heart or blood pressure issues.
Best answer:
Answer by Anonymous
Don’t take it then sleep. I had an allergic reaction to it, my throat closed up and I nearly died.
Know better? Leave your own answer in the comments!
{ 1 comment… read it below or add one }
Pseudoephedrine is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. It is used as a nasal/sinus decongestant and stimulant, or as a wakefulness-promoting agent.Mechanism of action: Pseudoephedrine is a sympathomimetic amine. Its principal mechanism of action relies on its indirect action on the adrenergic receptor system. The vasoconstriction that pseudoephedrine produces is believed to be principally an a-adrenergic receptor response.
Adverse effects: Common adverse drug reactions (ADRs) associated with pseudoephedrine therapy include: CNS stimulation, insomnia, nervousness, excitability, dizziness and anxiety. Infrequent ADRs include: tachycardia and/or palpitations. Rarely, pseudoephedrine therapy may be associated with mydriasis (blurred vision), hallucinations, arrhythmias, hypertension, seizures and ischemic colitis; as well as severe skin reactions known as recurrent pseudo-scarlatina, systemic contact dermatitis, and nonpigmenting fixed drug eruption. Pseudoephedrine, particularly in high doses, may also cause episodes of paranoid psychosis.[13] It has also been reported that pseudoephedrine, amongst other sympathomimetic agents, may be associated with the occurrence of stroke.
Precautions & Contraindications: It is recommended that pseudoephedrine not be used in patients with: diabetes mellitus, cardiovascular disease, severe or uncontrolled hypertension, severe coronary artery disease, prostatic hypertrophy, hyperthyroidism, closed angle glaucoma, or pregnant women. Patients who are prone to anxiety or panic attacks should use pseudoephedrine with caution, as anxiety and restlessness are common side effects, mostly due to the drug’s stimulant properties.
Since nasal congestion is considered to be a relatively minor ailment, alternatives are preferred in patients with these conditions. Appropriate alternatives may include saline sprays/instillations, depending on the patient’s condition. Topical decongestants should be used with caution and for no longer than three days to avoid Rhinitis medicamentosa.
People with bipolar disorder should use care when taking pseudoephedrine, as it can cause insomnia and thus trigger a manic episode. The in vitro addition of pseudoephedrine to sera containing the cardiac iso-enzyme MB of serum creatine phosphokinase progressively inhibits the activity of the enzyme. The inhibition becomes complete over 6 hours.
Good Luck…!!!